Purified Anti-Human CD159a Antibody[S19004C] (AN010020P)
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For research use only.
| Alternate Names | NKG, C lectin type II protein, CD159 antigen like family member A, CD159a antigen, Killer cell lectin like receptor subfamily C member 1, MGC13374, MGC59791, Natural killer cell lectin, Natural killer cell protein group 2-A1, Natural killer cell receptor NKG2A, Natural killer group protein 2, NKG2 1/B activating NK receptor, NKG2 A, NKG2 A/B activating NK receptor, NKG2 A/B type II integral membrane protein, NKG2 A/NKG2 B type II integral membrane protein, NKG2 B, NKG2-1/B activating NK receptor, NKG2A, NKG2B, rNKG2A, KLRC, KLRC1, CD159A, NKG2, NKG2A, CD159 antigen-like family member A, NK cell receptor A, NKG2-A/B-activating NK receptor, NKG2-A/NKG2-B type II integral membrane protein |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | CD159a, also known as NKG2A or KLRC1, is a type II transmembrane protein. It belongs to the killer cell lectin-like receptor family also known as the NKG2 family. It is expressed on NK and NKT cells and T cell subsets. NKG2A is an inhibitory NK cell receptor and it is expressed as a heterodimer with CD94. In human, NKG2A/CD94 complex interacts HLA-E on target cells and inhibits T cells and NK cell effector functions. Recent studies showed that NKG2A blockade enhances the anti-tumor effect of NK cell and CD8+ T cells. |
| Immunogen | Recombinant Human CD159a protein |
| Abbre | CD159a |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Cellular Localization |
Cell membrane
|
| Tissue Specificity |
Predominantly expressed in NK cells
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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